In the museum painting section, is gathered an important set of works done in Portugal during the XV to the XVIII century, of which, by its relevance, outstands a set of paintings of the primitive Portuguese method, namely, the Ecce Homo, a gothic board of S. Vicente, of the last of the XV century, attributed to Master Gil (Coimbra style), a Virgin of the Rose, attributed to the Portuguese painter Francisco Campos, the S. Gregorio mass book of the Masters de Ferreirim workshop (Gregorio Lopes?, the Virgin Annunciation), and a group of 4 boards, of Italian influence, from Portuguese painter Antonio Nogueira authorship, which represent several scenes of the life of Christ, namely the Visitation of Saint Isabel, the Descent of the Cross, the Resurrection and the Ascension.
Of the XVIII century Portuguese paintings, must be noted The Final Judgment, by Bento Coelho da Silveira, and the Last Supper, by Pedro Alexandrino.
Of the Flemish School can be seen the Virgin do Leite, oil on wood, dated from the first half of the XVI century, the triptych of Christ and the Apostles, also oil on wood, from the same first half of the XVI century.
Of the XVII century Spanish School of painting, the visitor can observe the Saint Agostino, the Martyrdom of S. Bartolomeo and the S. Jeronimo canvasses, attributed to Jose de Ribera, the Spanish painter.
Of Juan Arellano, Spanish painter of Santander city, belong a collection of two busts, one male, representing Christ, and one female, representing the Virgin. It is also worthy to note a Vanitas (oil on wood), of S. Francisco de Assis in trance, of S. Pedro de Alcantara, and two canvasses representing S. João Baptista head.